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An in vitro and in vivo study has shown the synergistic effect of all-trans-RA when combined with paclitaxel in A549 cell line

4.1 Rheumatoid arthritis The pathogenic process of RA, a systemic autoimmune disease characterized by persistent synovitis, involves the activation of an aberrant immune response and the breakdown of immune system tolerance (131)

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Sun H, Zhao F, Liu Y, Ma T, Jin H, Quan K, et al